N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine
نویسندگان
چکیده
The title compound, C(16)H(15)N(5), crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in mol-ecule A, and 6.8 (1) and 11.6 (9)° in mol-ecule B. The crystal packing is influenced by the collective action of weak inter-molecular N-H⋯N hydrogen bonds, a π-π stacking inter-action between neighbouring pyridyl rings of mol-ecule A [centroid-centroid distance = 3.8395 (10) Å] and C-H⋯π inter-actions.
منابع مشابه
4-{4-Methyl-2-[(methyl)(2-methylphenyl)amino]-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine
In the title compound, C(23)H(23)N(5)S, the thia-zole ring and pyrimidine ring are almost coplanar, making a dihedral angle of 4.02 (9)°. in the crystal, weak inter-molecular N-H⋯N inter-actions link pairs of molecules into centrosymmetric dimers.
متن کامل4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine
In the title compound, C(22)H(19)Cl(2)N(5)S, the thia-zole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°. In the crystal, intermolecular N-H⋯N hydrogen bonds link pairs of molecules into centrosymmetric dimers..
متن کاملN-(3-Methoxyphenyl)-4-{4-methyl-2-[(methyl)(4-methylphenyl)amino]-1,3-thiazol-5-yl}pyrimidin-2-amine
The asymmetric unit of the title compound, C(23)H(23)N(5)OS, contains two independent mol-ecules. In one mol-ecule, the thia-zole and pyrimidine rings are almost co-planar, making a dihedral angle of 2.48 (8)°. In the other mol-ecule, the corresponding dihedral angle is 12.82 (8)°. The crystal structure is stabilized by weak inter-molecular N-H⋯N and C-H⋯O inter-actions that extend along the b ...
متن کامل1-Amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidin-2(1H)-one
In the title compound, C(19)H(17)N(3)O(2), the dihedral angles between the pyrimidine ring and the two benzene rings are 34.87 (12) (for the directly-bonded ring) and 69.57 (12)°. An intra-molecular N-H⋯O hydrogen bond occurs. The crystal packing features inter-molecular N-H⋯O hydrogen bonds.
متن کاملPyrimidin-2-amine–1-phenylcyclopentane-1-carboxylic acid (1/1)
In the crystal structure of the title co-crystal, C(4)H(5)N(3)·C(12)H(14)O(2), the components are linked by N-H⋯O and O-H⋯N hydrogen bonds. Self-assembly of these dimeric units results in a four-component supra-molecular unit featuring a homosynthon between two mol-ecules of the pyrimidin-2-amine involving two N-H⋯O hydrogen bonds, and two heterosynthons between each one mol-ecule of pyrimidin-...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010